Editing in-built HTTP Response Headers

Is there a way to edit in-built HTTP Response Headers?

I am trying to edit the Cache-Control header in a IIS/8.5 server running .NET 3.5

The Cache-control header has a value "no-cache:set-cookie" and many clients are treating that as a no-cache directive. I want to remove the "no-cache:set-cookie" from the Cache-control header